Testosterone and DAA

Testosterone and DAA

Are you familiar with DAA? If you are then you are either a bodybuilder or someone desperately in search for a way to boost your testosterone. Fortunately, you are in the right track.


Identifying the main function

D-Aspartic acid aka DAA is an amino acid which functions to control hormonal output, not the least of which is testosterone. DAA is a non-essential amino acid, meaning that your body produces it naturally.  So, why aren’t your testosterone levels satisfyingly high yet?

Perhaps because DAA’s primary purpose is not to increase testosterone.  It functions mainly as a metabolite in the urea cycle and in the formation of glucose from non-carbohydrate substances, a process called gluconeogenesis. Some studies claim that DAA can increase testosterone levels but too few have proven its exact mechanism of action in men.  Nevertheless, let’s explore some of these studies.


Studies on DAA

A study performed in Italy in 2009 observed the effects of DAA in the release and synthesis of Luteinizing Hormone (LH) and testosterone in men. Forty-three participants were gathered in this study. Twenty-three were given an oral dose of DAA while the control group of twenty men was given a placebo, both for twelve consecutive days. LH and testosterone levels did not increase significantly after 6 days but the story is quite different after 12 days.  The test subjects experienced an increase of 33.3% in LH and 42% in Testosterone. That is good news.  More good news: D-Aspartic acid stays in the system for at least 3 days, meaning that your T-levels won’t start dropping for a little bit.  If you have Amazon prime, you might be able to order it the day you run out and get it in time!

It’s not hard to find studies that show that d-aspartic acid can increase testosterone levels in animals. This study and also this study conducted in rats, and this one on frogs and this one on lizards provided enough evidence that DAA plays an important role in the testosterone levels of our rodent and reptilian friends.  If you’re a boar, don’t take it.  There was a study conducted that showed it raises estrogen levels in boars.

DAA boosts testosterone in frogs.

DAA boosts testosterone in frogs.

It is safe to say that DAA really can help increase of testosterone, but the desired effect is seen only when taken in high doses. You will need at least 3,000 milligrams/day. Most brands of nutritional supplement carry capsules of just 35-600 mg each.

Health Benefits

Medically, D-aspartic acid is not well-known for its great contribution in health. If it helps to elevate your testosterone levels, you will get the usual array of benefits like increased libido, high energy levels, weight control and a positive emotional state as reported by The Mayo Clinic.

Side Effects

A peculiar side effect that should alarm men was demonstrated in this study. It investigated the effect of d-aspartic acid on aromatase activity in lizards. Aromatase is the enzyme responsible for the synthesis of estrogen. In this experiment, d-aspartic acid was administered in lizards causing a decrease in testosterone and increase in the conversion of testosterone to estradiol. In the presence of d-aspartic acid, aromatase was four times greater. Then again, this is a study done in lizards.

On the human side, you might experience headaches, but there is a lot more to worry about. The journal “Impulse” found that D-aspartic acid can cause seizures and increase the likelihood of Alzheimer’s disease due to excess activation of aspartate receptors. Risk for other nervous system disorders such as amyotrophic lateral sclerosis and Hungtington’s disease is elevated as well.

Lets put a human face on the potential side effects of D-Aspartic acid:

Read this Amazon review of a DAA product:

DAA Side Effect – Depression

That’s a major bummer.  I hope this poor guy recovers.


I have mixed feelings about it.  On the one hand, there is pretty convincing evidence that D-Aspartic acid works in increasing testosterone.  On the other hand, you have the case of the poor lad above.  My ruling: I’m going to try it but I’m going to be damn careful.  Definitely going to cycle it.

If you want to boost testosterone and stay on the safe side, as always, I recommend tongkat ali.

Did you know?
...that you can have the most up-to-the minute information on how to naturally increase your testosterone levels delivered to your mailbox?


  1. davidgmills says:

    My guess that what happened to this young man is that the body’s reserves of progesterone got depleted since testosterone is made from progesterone. Most of us are progesterone deficient to begin with.

    Progesterone is a great aromatase inhibitor and stops testosterone from turning to estrogen. It is also a 5 aplha reductase inhibitor and stops testosterone from turning into DHT.

    Progesterone is estrogen’s antagonist and when I was on testosterone therapy, progesterone immediately reversed the side effects I was having from an increase in estrogen (gynocomastia for one).

    Progesterone also prevents seizures and depression. It is the body’s brain and nerve system hormone.

    Natural bio-identical progesterone is what I think should be taken a long with d-aspartic acid to combat it’s side effects. Easily purchased online.

    • Hey David,

      Thanks for the comment. That’s huge. I haven’t looked into this at all as I have avoided using anything that is or behaves like exogenous hormones. I emphasize supplements that increase your body’s natural production of beneficial hormones. However, I’m going to look into bio-identical progesterone as you suggested and assess its potential benefits objectively.

Speak Your Mind


You might also likeclose